Early Clinical Failure Criteria
Begin by calculating the Early Clinical Failure Score
These criteria are evaluated after 72-96 hours of gram-negative BSI.
A “one-size-fits-all” treatment duration for gram-negative bloodstream infections (BSI) does not fit our high standards of antimicrobial therapy in the era of precision medicine.
These customized treatment durations are derived from a recent clinical trial results and re-analysis of our local data after stratification based on clinical response to antimicrobial therapy within the first 4 days of BSI.