Guidelines
Clostridium difficile Infection (CDI)

Clostridium difficile Infection (CDI)

This guideline is under construction

Laboratory Diagnostics

C. difficile Classification

Infection that has been diagnosed within three days of admission

Infection that has been diagnosed after the first three days of admission

Disease Severity

  • WBC <15 cells/mm³
  • SCr ≤1.5 mg/dL
  • WBC >15 cells/mm³
  • SCr >1.5 mg/dL (or 1.5x baseline)
  • Endoscopic or radiographic evidence of toxic megacolon
  • WBC >15 cells/mm³
  • SCr >1.5 mg/dL (or 1.5x baseline)
  • Endoscopic or radiographic evidence of toxic megacolon

Plus any of the following:

  • Hypotension or shock
  • Illeus
  • Megacolon
  • Admission to the ICU secondary to CDI