Refers to acute inflammation and subsequent infection of intestinal diverticula, usually of the sigmoid colon, affecting ~5% of patients with diverticulosis

Surgical/gastroenterology consultation for frank perforation, obstruction or fistula and refractory disease

Significant laboratory abnormalities may be absent

Blood cultures in severely ill and health care associated complicated infections; intra-operative cultures not needed unless hospital acquired or significant antibiotic exposure

Procalcitonin (PCT) not usually useful

If diarrhea (~25%), GPMP can be used to rule out other infectious etiologies (e.g. CDI, Salmonella spp.) but is unnecessary if diverticulitis is clear on imaging

Presence of colonic flora on urine culture suggests a colo-vesical fistula

Empiric Therapy