Ceftriaxone (Rocephin)
Renal

Renal

Not On Dialysis

CrCl greater than 15 mL/min

No dosing adjustment required

CrCl less than or equal to 15 mL/min

No dosage adjustment necessary

However, doses of greater than 2g/day have not been studied and should be done with close monitoring, especially in patients with concurrent hepatic dysfunction (decreased biliary excretion)