Therapy of gram negative infections including Pseudomonas, particularly in patients with penicillin and cephalosporin allergy or when there is no alternative susceptible agent.
Nebulized form used in cystic fibrosis patients.
Empiric therapy for febrile neutropenia.
Monitor liver enzymes.
Elevated liver enzymes
Cytopenias
Eosinophilia
Phlebitis at injection site
Rash/allergy
CNS toxicity
No significant interactions.
Antimicrobial class: Monobactam
Pregnancy category: B
Average serum half life: 2 hours
Urine penetration: Therapeutic
Lung penetration: Therapeutic
Biliary penetration: Moderate