General Spectrum of Activity
Skin and soft tissue infection (e.g. cellulitis).
Susceptible Staphylococcal, Streptococcal and gram negative infections.
Allergy (immediate or delayed).
Can cause positive Coombs, cytopenias, and hepatic and renal laboratory abnormalities.
Probenecid - prolonged half-life. Drug interaction has been used therapeutically to give once daily cefazolin.
Not recommended unless no other alternatives.
Antimicrobial class: 1st Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2 hours
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic