Guidelines
Ceftaroline (Adult)

Ceftaroline (Adult)

Note

Reserved for MRSA infections that cannot be treated with first-line agents

Monitor ANC due to risk of neutropenia

Dosing

Not on Dialysis:

CrCl (mL/min) Dose
>50 600 mg IV Q12h
30-50 400 mg IV Q12h
15-29 300 mg IV Q12h
<15 200 mg IV Q12h

Dialysis:

  Dose
CRRT 400 mg IV Q12h
Intermittent HD 200 mg IV Q12h

Not on Dialysis:

CrCl (mL/min) Dose
>50 600 mg IV Q8h
30-50 400 mg IV Q8h
15-29 300 mg IV Q8h
<15 200 mg IV Q8h

Dialysis:

  Dose
CRRT 400 mg IV Q8h
Intermittent HD 200 mg IV Q8h