Penicillin VK (oral)

C difficile risk
Oral Bioavailability


General Information

Penicillin VK (and Penicillin G) remain universally effective against Group A and other beta-hemolytic Strep (Groups B, C, & G).

Although the bioavailability of Penicillin VK is "moderate" the maximum oral dose is insufficient in many cases to treat severe disease, especially at sites with limited penetration (i.e. CNS, bone, synovial fluid). Consider IV Penicillin G for these instances.

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