Nitrofurantoin

C difficile risk
Low
Oral Bioavailability
Moderate
Cost
$

Spectrum Of Activity

Dosing

Contraindicated in infants < 1 month of age.

General Information

Does not provide adequate systemic concentrations for treatment of systemic infections (i.e urosepsis, pyelonephritis); appropriate for uncomplicated and complicated cystitis. Reduced efficacy in patients with severe renal impairment. Contraindicated in infants less than 1 month of age (risk of hemolytic anemia), moderate-severe renal impairment, G-6-PD deficiency. Do not use near term in pregnancy.

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