Antimicrobials
Azithromycin

Azithromycin

Spectrum of Activity

Dosing

General Information

  • Prolongation of QTc interval
  • Diarrhea
  • Pyloric stenosis (infantile hypertrophic pyloric stenosis, IHPS) has been reported with erythromycin and azithromycin in infants less than 6 weeks

While less risk of interaction compared to other macrolides, several potential CYP450 interactions may occur; consult a pharmacist for for more details.

Avoid concurrent use with other drugs that prolong QTc

Monitor for signs or symptoms of infantile hypertrophic pyloric stenosis (IHPS) if infant under 6 weeks of life.

Azithromycin is still the drug of choice for treatment or prophylaxis of pertussis as the risk of developing severe pertussis outweighs the potential risk of IHPS.

Concentration: 40 mg/mL

Taste: Bitter taste

Not all strengths of oral liquids are listed nor be available on the CHEO Formulary

  • 250 mg
  • 600 mg

Tablets or capsules are preferred especially over an unpleasant tasting oral liquid.

Not all strengths of oral tablets/capsules are listed and they are not all available on the CHEO Formulary.