Antimicrobials
Clarithromycin

Clarithromycin

Dosing

Oral Dosing

Daily Dose: 15 mg/kg/day

Maximum Daily Dose: 1000 mg/day

Dosing Frequency: PO divided BID

General Information

  • Prolongation of QTc interval

  • Elevated liver enzymes

  • Diarrhea

  • Substrate of CYP3A4.

  • Multiple CYP450 interactions possible - consult a pharmacist for more detail.

  • May increase digoxin, carbamazepine level.

  • Use caution with QTc prolonging medications.

Treatment of proven or suspected pertussis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae

Concentration: 50 mg/mL

Taste: Good

Not all strengths of oral liquids are listed nor be available on the CHEO Formulary

  • 250 mg

  • 500 mg

Tablets or capsules are preferred especially over an unpleasant tasting oral liquid.

Not all strengths of oral tablets/capsules are listed and they are not all available on the CHEO Formulary.