Candida infections both mucocutaneous and invasive - i.e. Candidemia
Antifungal prophylaxis in immunocompromised
Therapeutic drug monitoring may be helpful to ensure adequate concentrations and exclude toxicity (discuss with ID)
QTc interval in patients at elevated risk
Monitor hepatic profile
CYP450 interactions ++
Other QTc prolonging agents
Recommend review of pt medications due to high frequency of significant interactions
Antimicrobial class: Triazole antifungal, second generation
Pregnancy category: D
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Poor
